Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(±)10(11)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 0.43 and 22.5 nM for CB1 and CB2 receptors, respectively). It is produced though direct epoxygenation of docosahexaenoyl ethanolamide by cytochrome P450 (CYP) epoxygenases. 10,11-EDP epoxide (12.5 and 25 μM) reduces the viability of 143B metastatic osteosarcoma cells. It induces apoptosis and inhibits cell migration in a wound-healing assay in 143B, MG63, and HOS osteosarcoma cells. (±)10(11)-EDP ethanolamide also reduces tube formation by human umbilical vein endothelial cells (HUVECs) in a Matrigel assay.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 μg | 35 days | $ 223.00 | |
50 μg | 35 days | $ 420.00 | |
100 μg | 35 days | $ 788.00 |
Description | (±)10(11)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 0.43 and 22.5 nM for CB1 and CB2 receptors, respectively). It is produced though direct epoxygenation of docosahexaenoyl ethanolamide by cytochrome P450 (CYP) epoxygenases. 10,11-EDP epoxide (12.5 and 25 μM) reduces the viability of 143B metastatic osteosarcoma cells. It induces apoptosis and inhibits cell migration in a wound-healing assay in 143B, MG63, and HOS osteosarcoma cells. (±)10(11)-EDP ethanolamide also reduces tube formation by human umbilical vein endothelial cells (HUVECs) in a Matrigel assay. |
Molecular Weight | 387.564 |
Formula | C24H37NO3 |
CAS No. | 2123484-71-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 50 mg/mL
Ethanol: 50 mg/mL
Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL
DMSO: 50 mg/mL
You can also refer to dose conversion for different animals. More
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(±)10(11)-EDP Ethanolamide 2123484-71-7 (±)10(11)EDP Ethanolamide 10(11)-EDP Ethanolamide (±)10(11) EDP Ethanolamide inhibitor inhibit