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Compound Libraries Bioactive Compound Library

Bioactive Compound Library

Catalog No. L4000
  Library Compound List   Excel SDF

It contains more than 8829 small molecule compounds, with known biological activities causing biological reaction in cells, tissue even whole body, including Clinical compound library (L3400), Preclinical compound library (L3410), and Approved drug library (L1000). All compounds have clear targets and detailed information description, which is the key point to drug research and development like drug repurposing, small molecule inducing stem cell differentiation, and target identification in mechanism interrogation.

Many scientists have identified small molecules that can regulate cell fate and function, and stem cell differentiation by screening annotated bioactive compound library with confirmed activity and known targets. Recent advances in iPSC technology have made reprogramming of somatic cells towards pluripotency possible and simpler. Using both phenotypic screening and hypothesis-driven approaches, a growing number of compounds have been identified that can functionally replace reprogramming transcription factors, enhance efficiency of iPSC generation and accelerate the reprogramming process by single use or a combination of several molecules with success in cardiomyocyte differentiation and proliferation, neural progenitor cells, etc.

In the library, we provide the peptides and other drug molecules with low solution stability in the form of dry powder (set as Part B) in order to ensure the best using effect of the compound library and increase the probability of successful screening as much as possible.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 65982.00
250 μL * 10 mM (in DMSO) 109966.00
1 mg 109966.00
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Product Description

  • A collection of 8829 small molecule compounds with validated activity for high throughput screening (HTS), high content screening (HCS), cell induction, and target identification;
  • All compounds have clear targets;
  • An effective tool for discovering new with old drugs, cell induction, and new drug target screening;
  • Covers various disease research areas, such as Cancer, Metabolism, Immunology and Cardiovascular system, etc.
  • Detailed compound information with structure, target, activity, IC50 value, and brief introduction;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L4000)

Library Composition

AChR (220)
5-HT Receptor (196)
Antibacterial (195)
COX (169)
Endogenous Metabolite (164)
Adrenergic Receptor (157)
Antibiotic (148)
Dopamine Receptor (129)
PI3K (127)
CDK (121)
DNA/RNA Synthesis (120)
NF-κB (115)
EGFR (111)
VEGFR (107)
Potassium Channel (105)
Autophagy (105)
Antioxidant (92)
Apoptosis (92)
Calcium Channel (91)
Histamine Receptor (90)
Sodium Channel (89)
Dehydrogenase (85)
Estrogen/progestogen Receptor (84)
P450 (84)
GABA Receptor (81)
Epigenetic Reader Domain (79)
HDAC (78)
PDE (77)
TNF (75)
HIV Protease (74)
PPAR (73)
JAK (68)
GluR (67)
Src (67)
Antifungal (66)
ERK (64)
Histone Methyltransferase (64)
Topoisomerase (63)
Microtubule Associated (62)
mTOR (62)
Antifection (61)
TRP/TRPV Channel (61)
Bcr-Abl (60)
FGFR (60)
PDGFR (60)
Glucocorticoid Receptor (59)
Akt (59)
RAAS (59)
Opioid Receptor (58)
PKC (56)
FLT (54)
p38 MAPK (53)
IL Receptor (53)
STAT (53)
BCL (51)
ROS (49)
Raf (49)
Wnt/beta-catenin (47)
c-Kit (47)
Caspase (46)
GPR (46)
Androgen Receptor (45)
c-Met/HGFR (45)
AMPK (43)
GR (43)
PARP (43)
MAO (43)
NMDAR (42)
ALK (42)
ATPase (42)
Prostaglandin Receptor (41)
GSK-3 (39)
HSP (39)
Vitamin (38)
Tyrosinase (38)
MMP (37)
Antiviral (37)
MEK (36)
Tyrosine Kinases (36)
HCV Protease (35)
TLR (34)
Parasite (33)
Glucokinase (33)
NOS (32)
DNA-PK (32)
Aurora Kinase (31)
IκB/IKK (31)
Phosphatase (31)
Beta Amyloid (30)
BTK (29)
Adenosine Receptor (29)
JNK (29)
ribosome (29)
Sirtuin (28)
TGF-beta/Smad (28)
Integrin (28)
p53 (28)
Carbonic Anhydrase (28)
Influenza Virus (27)
Lipoxygenase (27)
Proteasome (27)
Phospholipase (26)
TAM Receptor (26)
HIF (26)
P2 Receptor (26)
CXCR (25)
Cysteine Protease (25)
PKA (25)
Trk receptor (24)
ATM/ATR (24)
Apoptosis inducer (24)
HER (24)
Norepinephrine (23)
DNA Alkylation (23)
c-RET (23)
Gamma-secretase (23)
S6 Kinase (23)
ROCK (22)
Serine Protease (22)
Retinoid Receptor (22)
CaMK (22)
Cannabinoid Receptor (22)
Casein Kinase (21)
CCR (21)
Amino Acids and Derivatives (21)
MAPK (21)
Histone Demethylase (21)
Hedgehog/Smoothened (20)
Mdm2 (20)
DUB (20)
Ras (20)
S1P Receptor (20)
PLK (19)
Neurokinin receptor (19)
IGF-1R (19)
NADPH (18)
Nrf2 (18)
Chloride channel (18)
P-gp (18)
Reductase (18)
Syk (17)
Transferase (17)
FAK (17)
AhR (17)
NOD (17)
LRRK2 (17)
HMG-CoA Reductase (17)
Immunology & Inflammation related (16)
FXR (16)
Chk (16)
Thyroid hormone receptor(THR) (16)
Reverse Transcriptase (16)
Serine/threonin kinase (15)
Sigma receptor (15)
c-Myc (15)
FAAH (15)
HBV (15)
MRP (15)
GNRH Receptor (14)
IDO (14)
DPP-4 (14)
Thrombin (14)
Protease-activated Receptor (14)
Rho (13)
SGLT (13)
DNA gyrase (13)
DNA Methyltransferase (13)
CFTR (13)
E1/E2/E3 Enzyme (13)
Glucagon Receptor (13)
HSV (13)
Mitochondrial Metabolism (13)
LTR (12)
OX Receptor (12)
DHFR (12)
Aromatase (12)
BACE (12)
Proton pump (12)
Pim (12)
STING (11)
transporter (11)
Vasopressin Receptor (11)
c-Fms (11)
Fatty Acid Synthase (11)
Ferroptosis (11)
Endothelin Receptor (11)
HIF/HIF Prolyl-Hydroxylase (11)
Hydroxylase (10)
Liver X Receptor (10)
Lipase (10)
Kinesin (10)
NO Synthase (10)
PDK (10)
Melanocortin Receptor (10)
Neuropeptide Y Receptor (10)
Factor Xa (10)
CSF-1R (10)
SARS-CoV (10)
PERK (10)
ROR (9)
cAMP (9)
Nucleoside Antimetabolite/Analog (9)
GPCR19 (9)
GHSR (9)
Histone Acetyltransferase (8)
LPA Receptor (8)
PAK (8)
ABC (8)
PKM (8)
UGT (7)
CAT (7)
Gap Junction Protein (7)
PAI-1 (7)
Monocarboxylate transporter (7)
Lipid (7)
IAP (7)
LDL (6)
IRE1 (6)
Guanylate cyclase (6)
MPO (6)
NAMPT (6)
Estrogen Receptor/ERR (6)
Ephrin Receptor (6)
Discoidin Domain Receptor (DDR) (6)
Bradykinin Receptor (6)
Arginase (6)
Acetyl-CoA Carboxylase (6)
Aminopeptidase (6)
Annexin A (6)
Platelet aggregation (6)
Phosphorylase (6)
Telomerase (6)
SGK (5)
Porcupine (5)
BMI-1 (5)
CaSR (5)
DNA (5)
DprE1 (5)
CETP (5)
Complement System (5)
DYRK (5)
Free radical scavengers (5)
NADPH-oxidase (5)
Monoamine Transporter (5)
MLK (5)
PD-1/PD-L1 (5)
p97 (5)
PAD (5)
GRK (5)
LIM Kinase (5)
iGluR (4)
GST (4)
GTPase (4)
Hck (4)
Oxytocin Receptor (4)
PED (4)
NPC1L1 (4)
OCT (4)
MNK (4)
Neprilysin (4)
Neurotensin Receptor (4)
Dynamin (4)
cholecystokinin (4)
Decarboxylase (4)
cell cycle arrest (4)
ATP Citrate Lyase (4)
Acyltransferase (4)
advanced glycation end products (4)
PGE Synthase (4)
PTEN (4)
PYK2 (4)
Reactive Oxygen Species (4)
Serotonin Transporter (4)
Tie-2 (4)
Xanthine Oxidase (4)
Wee1 (3)
Wnk (3)
SIK (3)
Smo (3)
Survivin (3)
Somatostatin (3)
AChE (3)
ACAT (3)
ACK (3)
Antifolate (3)
ASK (3)
Cell wall (3)
Carboxypeptidase(CPG2) (3)
Deubiquitinase (3)
CRM1 (3)
Na-K-Cl cotransporter (3)
MT Receptor (3)
MTH1 (3)
Monoamine Oxidase (3)
Mitophagy (3)
lysosomal autophagy (3)
OXPHOS (3)
PAFR (3)
Hippo pathway (3)
GlyT (3)
GPX (3)
Interleukin Related (3)
Integrase (2)
Indoleamine 2,3-Dioxygenase (IDO) (2)
IRAK (2)
KSP (2)
gp120/CD4 (2)
Haspin Kinase (2)
Hexokinase (2)
P2X Receptor (2)
OAT (2)
Melanin-concentrating Hormone Receptor (MCHR) (2)
Melatonin Receptor (2)
MicroRNA (2)
Myosin (2)
CRFR (2)
CGRP Receptor (2)
Dehydrogenase inhibitor (2)
DNA Alkylator/Crosslinker (2)
EBI2/GPR183 (2)
Electron transport (2)
FLAP (2)
GluCls (2)
Glutaminase (2)
Glutathione Peroxidase (2)
Glutathione reductase (2)
Aryl Hydrocarbon Receptor (2)
Bombesin Receptor (2)
BCRP (2)
Anti-infection (2)
Thrombopoietin Receptor (2)
RSV (2)
RIP kinase (2)
PI4K (2)
TOPK (2)
VDA (2)
VDAC (2)
TSH Receptor (2)
Transaminase (1)
Virus Protease (1)
YAP (1)
Progesterone Receptor (1)
PTP1B (1)
RAR/RXR (1)
Salt-Inducible Kinase (1)
Thioredoxin (1)
TACC (1)
Stearoyl-CoA Desaturase (SCD) (1)
Stemness kinase (1)
stilbene oxidase (1)
Aquaporin (1)
APC (1)
Apelin receptor (1)
Anion Exchanger (1)
aconitase (1)
Adenylyl cyclase (1)
Adiponectin receptor (1)
Beta-Secretase (1)
BVDV (1)
FOXO1 (1)
FABP (1)
Epoxide Hydrolase (1)
DNA Stain (1)
CPT (1)
Na+/Ca2+ Exchanger (1)
N-Acetylglucosaminyltransferase (1)
MyD88 (1)
Motilin Receptor (1)
MELK (1)
MALT (1)
NOD-like Receptor (NLR) (1)
NMU2R (1)
NKCC (1)
Histone Acetylation (1)
HCN Channel (1)
hCE (1)
GSNOR (1)
Keap1-Nrf (1)
Isocitrate Dehydrogenase (IDH) (1)
Leukotriene Receptor (1)
LHRH (1)
IP3 Receptor  (1)
IFNAR (1)
Hydrogenase (1)