Cart
Compound Libraries Autophagy Compound Library

Autophagy Compound Library

Catalog No. L3200
  Library Compound List   Excel SDF

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. Targeted damaged cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. Autophagy, cellular senescence, and apoptosis are three key responses of a cell facing a stress, correlating with each other. It has been reported that defects of autophagy are associated with genomic damage, metabolic stress, and tumorigenesis. The Autophagy Compound library by TargetMol contains 1067 compounds with defined autophagy-inducing or -inhibitory activity, and is a useful tool for studying the roles of pro- and anti-autophagic molecules in cells as well as for use in in-vitro applications.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 11792.00
250 μL * 10 mM (in DMSO) 20052.00
1 mg 20052.00
Request Library
Get quote

Product Description

  • A unique collection of 1067 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L3200)

Library Composition

Autophagy (99)
PI3K (88)
mTOR (57)
AMPK (38)
HDAC (37)
Akt (29)
Bcr-Abl (27)
Raf (27)
p38 MAPK (26)
NF-κB (25)
CXCR (24)
VEGFR (24)
Aurora Kinase (23)
CDK (22)
ERK (22)
DNA-PK (21)
Calcium Channel (21)
MEK (21)
p53 (21)
c-Kit (20)
EGFR (20)
DNA/RNA Synthesis (19)
Adrenergic Receptor (19)
Src (19)
COX (18)
FLT (18)
LRRK2 (17)
GSK-3 (16)
AChR (16)
PDGFR (16)
PKC (15)
Apoptosis (15)
TNF (14)
Potassium Channel (13)
P450 (13)
FGFR (13)
JAK (13)
Mdm2 (13)
Microtubule Associated (12)
BCL (12)
5-HT Receptor (12)
Estrogen/progestogen Receptor (12)
PKA (12)
Sodium Channel (12)
S6 Kinase (12)
Retinoid Receptor (11)
Dopamine Receptor (11)
CFTR (10)
CaMK (10)
ATM/ATR (10)
Sirtuin (10)
STAT (9)
Topoisomerase (9)
Proteasome (9)
c-RET (9)
DUB (9)
MMP (9)
JNK (9)
Epigenetic Reader Domain (9)
Glucocorticoid Receptor (8)
HIF (8)
HMG-CoA Reductase (8)
ATPase (8)
Antibiotic (8)
PPAR (8)
PDE (8)
Trk receptor (8)
Tyrosine Kinases (7)
PERK (7)
Antibacterial (7)
FAAH (7)
c-Met/HGFR (7)
Casein Kinase (7)
Caspase (7)
HSP (7)
HIV Protease (7)
IL Receptor (7)
Histone Methyltransferase (6)
Histamine Receptor (6)
GR (6)
Dehydrogenase (6)
Apoptosis inducer (6)
Serine/threonin kinase (6)
ROCK (5)
TGF-beta/Smad (5)
PARP (5)
Antioxidant (5)
DNA Alkylation (5)
Cysteine Protease (5)
FXR (5)
GABA Receptor (5)
HER (5)
NADPH (5)
MRP (4)
Mitophagy (4)
MAO (4)
IGF-1R (4)
IκB/IKK (4)
Carbonic Anhydrase (4)
DNA Methyltransferase (4)
Androgen Receptor (4)
ALK (4)
Amino Acids and Derivatives (4)
PDK (4)
Phospholipase (4)
TLR (4)
transporter (4)
ROS (4)
Serine Protease (4)
Rho (4)
ribosome (3)
PTEN (3)
RAAS (3)
SGK (3)
Phosphatase (3)
Pim (3)
Parasite (3)
NOS (3)
TRP/TRPV Channel (3)
Vitamin (3)
ABC (3)
Adenosine Receptor (3)
BTK (3)
DPP-4 (3)
DHFR (3)
Endogenous Metabolite (3)
c-Fms (3)
c-Myc (3)
Lipoxygenase (3)
lysosomal autophagy (3)
MAPK (3)
HIF/HIF Prolyl-Hydroxylase (3)
Hedgehog/Smoothened (3)
E1/E2/E3 Enzyme (3)
Fatty Acid Synthase (3)
Glucokinase (3)
GluR (3)
GPR (2)
GTPase (2)
Gamma-secretase (2)
Hck (2)
HCV Protease (2)
HSV (2)
MLK (2)
MNK (2)
NMDAR (2)
LTR (2)
LDL (2)
IDO (2)
CCR (2)
Cannabinoid Receptor (2)
Dynamin (2)
FAK (2)
Beta Amyloid (2)
BMI-1 (2)
BACE (2)
Antiviral (2)
Annexin A (2)
AhR (2)
VDA (2)
Tyrosinase (2)
Nrf2 (2)
Norepinephrine (2)
Opioid Receptor (2)
p97 (2)
PLK (2)
Prostaglandin Receptor (2)
Ras (2)
Reductase (2)
SIK (2)
TAM Receptor (2)
Survivin (1)
Syk (1)
Transferase (1)
Thrombin (1)
Tie-2 (1)
TOPK (1)
Reverse Transcriptase (1)
Sigma receptor (1)
ROR (1)
Salt-Inducible Kinase (1)
SARS-CoV (1)
Proton pump (1)
P-gp (1)
PAFR (1)
PAI-1 (1)
OXPHOS (1)
P2 Receptor (1)
Nucleoside Antimetabolite/Analog (1)
NPC1L1 (1)
UGT (1)
Vasopressin Receptor (1)
Antifection (1)
ACK (1)
Aminopeptidase (1)
ATP Citrate Lyase (1)
Arginase (1)
Aromatase (1)
DNA (1)
DNA gyrase (1)
CAT (1)
Chk (1)
CSF-1R (1)
iGluR (1)
Immunology & Inflammation related (1)
Integrin (1)
IRAK (1)
Lipase (1)
Lipid (1)
NOD (1)
MPO (1)
Mitochondrial Metabolism (1)
Melatonin Receptor (1)
IAP (1)
Histone Demethylase (1)
FOXO1 (1)
Ferroptosis (1)
HBV (1)
GRK (1)