2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP2135L | CAC 253 acetate | cAC 253 acetate (TP2135 Free base) | Amylin Receptor |
cAC 253 acetate (TP2135 Free base) is an amylin antagonist. cAC 253 acetate inhibits 125I-adrenomedullin binding, with an IC50 of 25 nM. | |||
TP2135 | CAC 253 | ||
Amylin (AMY3) antagonist (IC50 = 0.3 μM). Protects neuronal cells from Aβ(1-42)-induced cytotoxicity in vitro. Brain penetrant. Improves spatial memory and reduces Aβ plaque number and total area in a mouse Alzheimer's d... |