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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16884 | Silvestrol | (-)-Silvestrol | Others |
Silvestrol is a eukaryotic translation initiation factor 4A inhibitor. Silvestrol causes autophagy and caspase-mediated apoptosis. | |||
T12916 | Silvestrol aglycone | Others | |
Silvestrol aglycone is an analogue of Silvestrol, inhibits protein translation initiation in cancer cells(EC50s of 10 and 200 nM for myc-LUC and tub-LUC luciferase reporter protein translation, respectively), with nti-ca... | |||
T12915 | Silvestrol aglycone (enantiomer) | Others | |
Silvestrol aglycone (enantiomer) is a cyclopenta benzofuran core phenol. | |||
T11215 | Episilvestrol | Others | |
Episilvestrol is a specific eIF4A-targeting translation inhibitor, with antitumor activity. Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia silvestris. | |||
T72944 | EIF4A3-IN-18 | ||
eIF4A3-IN-18, a silvestrol analogue, disrupts the formation of the eIF4F translation complex, exhibiting EC 50 values of 0.8, 35, and 2 nM for myc-LUC, tub-LUC, and the growth inhibition of MBA-MB-231 cells, respectively... | |||
T73001 | EIF4A3-IN-9 | ||
eIF4A3-IN-9, a silvestrol analogue, disrupts the assembly of the eIF4F translation complex, exhibiting EC50 values of 29, 450, and 80 nM for myc-LUC, tub-LUC, and growth inhibition in MBA-MB-231 cells, respectively. It i... | |||
T72943 | EIF4A3-IN-17 | ||
eIF4A3-IN-17, a silvestrol analogue, disrupts the assembly of the eIF4F translation complex, exhibiting EC50 values of 0.9, 15, and 1.8 nM for myc-LUC, tub-LUC, and growth inhibition of MBA-MB-231 cells, respectively. Th... |