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20

Compounds

Cat No. Product Name Synonyms Targets
T6741 SPDP SPDP Crosslinker Others
SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could ...
T38597 SPDP-sulfo
SPDP-sulfo is a cleavable linker vital in ADC synthesis. SPDP-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing AD...
T17834 DM4-SPDP Others
DM4-SPDP, a drug-linker conjugate, integrates the antitubulin agent DM4 with the linker SMCC, facilitating the creation of antibody drug conjugates[1]. Additionally, SPDP serves as a short-chain crosslinker enabling amin...
T18535 PEG4-SPDP Others
PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
T18715 SPDP-PEG7-acid Others
SPDP-PEG7-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi...
T18714 SPDP-PEG5-acid Others
SPDP-PEG5-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi...
T18713 SPDP-PEG36-NHS ester Others
SPDP-PEG36-NHS ester is a PEG ADC linker consisting of 36 units, characterized by cleavability. It plays a crucial role in the synthesis of antibody-drug conjugates (ADCs)[1].
T18710 SPDP-PEG12-NHS ester Others
SPDP-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys...
T18709 SPDP-PEG12-acid Others
SPDP-PEG12-acid is a cleavable 12-unit polyethylene glycol (PEG) linker utilized for the synthesis of antibody-drug conjugates (ADCs)[1].
T15724 LC-PEG8-SPDP Others
LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
T18711 SPDP-PEG24-acid Others
SPDP-PEG24-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system w...
T18716 SPDP-PEG9-acid Others
SPDP-PEG9-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi...
T16916 SPDP-PEG4-acid Others
SPDP-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi...
T18725 Sulfo-LC-SPDP Others
Sulfo-LC-SPDP is a heterobifunctional crosslinker characterized by its thiol-cleavable and membrane impermeable properties.
T16918 SPDP-PEG6-NHS ester Others
SPDP-PEG6-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst...
T18712 SPDP-PEG24-NHS ester Others
SPDP-PEG24-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys...
T18525 PC SPDP-NHS carbonate ester Others
PC SPDP-NHS carbonate ester is a cleavable linker compound utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
T16915 SPDP-C6-NHS ester Others
SPDP-C6-NHS ester is an alkyl/ether-based linker utilized in the synthesis of PROTACs[1].
T16917 SPDP-PEG4-NHS ester Others
SPDP-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst...
T18733 Sulfo-SPDP-C6-NHS sodium Others
Sulfo-SPDP-C6-NHS sodium is a sodium salt form of a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
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