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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6741 | SPDP | SPDP Crosslinker | Others |
SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could ... | |||
T38597 | SPDP-sulfo | ||
SPDP-sulfo is a cleavable linker vital in ADC synthesis. SPDP-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing AD... | |||
T17834 | DM4-SPDP | Others | |
DM4-SPDP, a drug-linker conjugate, integrates the antitubulin agent DM4 with the linker SMCC, facilitating the creation of antibody drug conjugates[1]. Additionally, SPDP serves as a short-chain crosslinker enabling amin... | |||
T18535 | PEG4-SPDP | Others | |
PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs). | |||
T18715 | SPDP-PEG7-acid | Others | |
SPDP-PEG7-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi... | |||
T18714 | SPDP-PEG5-acid | Others | |
SPDP-PEG5-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi... | |||
T18713 | SPDP-PEG36-NHS ester | Others | |
SPDP-PEG36-NHS ester is a PEG ADC linker consisting of 36 units, characterized by cleavability. It plays a crucial role in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T18710 | SPDP-PEG12-NHS ester | Others | |
SPDP-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys... | |||
T18709 | SPDP-PEG12-acid | Others | |
SPDP-PEG12-acid is a cleavable 12-unit polyethylene glycol (PEG) linker utilized for the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T15724 | LC-PEG8-SPDP | Others | |
LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1]. | |||
T18711 | SPDP-PEG24-acid | Others | |
SPDP-PEG24-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system w... | |||
T18716 | SPDP-PEG9-acid | Others | |
SPDP-PEG9-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi... | |||
T16916 | SPDP-PEG4-acid | Others | |
SPDP-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi... | |||
T18725 | Sulfo-LC-SPDP | Others | |
Sulfo-LC-SPDP is a heterobifunctional crosslinker characterized by its thiol-cleavable and membrane impermeable properties. | |||
T16918 | SPDP-PEG6-NHS ester | Others | |
SPDP-PEG6-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst... | |||
T18712 | SPDP-PEG24-NHS ester | Others | |
SPDP-PEG24-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys... | |||
T18525 | PC SPDP-NHS carbonate ester | Others | |
PC SPDP-NHS carbonate ester is a cleavable linker compound utilized in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T16915 | SPDP-C6-NHS ester | Others | |
SPDP-C6-NHS ester is an alkyl/ether-based linker utilized in the synthesis of PROTACs[1]. | |||
T16917 | SPDP-PEG4-NHS ester | Others | |
SPDP-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst... | |||
T18733 | Sulfo-SPDP-C6-NHS sodium | Others | |
Sulfo-SPDP-C6-NHS sodium is a sodium salt form of a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1]. |