3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T34628 | SG3199 | SG 3199,SG-3199 | |
SG3199 is a PBD dimer which binds in the minor groove of DNA, and forms covalent DNA interstrand cross-links in naked linear plasmid DNA. SG3199 is potently cytotoxic against a panel of human solid tumour and haematologi... | |||
T77813 | SG3199-Val-Ala-PAB | ||
SG3199-Val-Ala-PAB is an intermediate in the synthesis of Tesirine, a conjugate of agent-linker for antibody-drug conjugates (ADCs), utilized in the research of various cancers [1]. | |||
T77086 | Mipasetamab uzoptirine | ||
Mipasetamab uzoptirine (ADCT-601) is an antibody-drug conjugate (ADC) targeting AXL. It combines a humanized anti-AXL antibody with a cleavable linker and the potent pyrrolobenzodiazepine (PBD) dimer cytotoxin SG3199. Mi... |