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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T69830 | GSK2239633 | ||
GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2... | |||
T69832 | RPR203494 | ||
RPR203494 is a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency. | |||
T69831 | RPR-200765A Mesylayte | ||
RPR-200765A is a potent and selective inhibitor of p38 MAP kinase (IC50 = 50 nM). It inhibits LPS-stimulated TNFalpha release both in vitro, from human monocytes (EC50 = 110 nM), and in vivo in Balb/c mice (ED50 = 6 mg/k... |