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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T62723 | RIPK1-IN-12 | ||
RIPK1-IN-12 is a potent inhibitor of RIPK1, which exhibits an inhibitory effect on necroptosis in human and mouse cells with EC50 values of 1.6 and 2.9 nM, respectively. | |||
T60316 | AV123 | ||
AV123 (compound 12) is a non-cytotoxic RIPK1 inhibitor with IC 50 of 12.12 μM. AV123 blocks the TNF-α-induced necroptotic with EC 50 of 1.7 μM, but not the apoptotic cell death. AV123 can be used in the study of necrotic... |