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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63583 | RET-IN-11 | ||
RET-IN-11 is a potent and selective RET inhibitor that acts on RET (IC50: 6.20 nM) and RETV804M (IC50: 18.68 nM).RET-IN-11 induces apoptosis.RET-IN-11 exhibits anti-proliferative and migratory effects in LC-2/ad cells. R... | |||
T78871 | PLM-101 | ||
PLM-101 is an anticancer compound orally active against acute myeloid leukemia by targeting FLT3 and RET. It impedes RET function, promoting autophagic breakdown of FLT3, and suppresses the PI3K and Ras/ERK pathways, con... |