2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T74814 | PKM2/PDK1-IN-1 | ||
PKM2/PDK1-IN-1, a shikonin thioether derivative, serves as a dual inhibitor for PKM2/PDK1. This compound effectively inhibits the proliferation and induces apoptosis in NSCLC cells. It promotes intercellular ROS producti... | |||
T81446 | PKM2 activator 6 | ||
Compound Z10 (PKM2 activator 6) serves as both a PKM2 activator and a PDK1 inhibitor, exhibiting dissociation constants (K D ) of 121 μM and 19.6 μM, respectively. It promotes apoptosis in colorectal cells while suppress... |