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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35889 | PB2 | ||
PB2, a tris(2-carboxyethyl)phosphine (TCEP) analogue, enhances the survival of retinal ganglion cells (RGCs) following axotomy in vitro. Even at nanomolar and picomolar concentrations, PB2 demonstrates pronounced efficac... | |||
T39176 | PB28 | ||
PB28 is a cyclohexylpiperazine derivative that functions as a potent and highly selective agonist of the sigma 2 (σ2) receptor, exhibiting a Ki (binding affinity) of 0.68 nM. At the same time, PB28 acts as an antagonist ... | |||
T23122 | PB28 dihydrochloride | PB 28 dihydrochloride | Others |
σ2 receptor agonist | |||
T4377 | Pimodivir | VX-787 | Influenza Virus |
Pimodivir (VX-787), an influenza A virus polymerases inhibitor via oral, interacts with the viral PB2 subunit. | |||
T12526 | PP7 | Influenza Virus | |
PP7 is a potent inhibitor of PB1-PB2 interaction(IC50 of 8.6 μM). | |||
T4377L | Pimodivir HCl | Pimodivir hydrochloride hemihydrate,Pimodivir hydrochloride | |
Pimodivir is an inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. The cell-based EC50 for VX-787 is 1.6 nM in a cytopathic effect (CPE) assay.... | |||
T83251 | 7-51A | Influenza Virus | |
7-51A is an effective inhibitor of the PB2 subunit of the influenza RNA-dependent RNA polymerase (RdRP), with a dissociation constant (K_D) of 1.64 nM as determined by isothermal titration calorimetry (ITC). | |||
T70207 | Pimodivir tosylate | ||
Pimodivir, also known as VX-787, JNJ-872, is a novel inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. VX-787 binds the cap-binding domain of ... | |||
T36734 | Methyl brevifolincarboxylate | ||
Methyl brevifolincarboxylate (Brevifolincarboxylic acid methyl ester) is a potent influenza virus PB2 cap-binding inhibitor. Methyl brevifolincarboxylate exhibits inhibitory activity against influenza virus A/Puerto Rico... |