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Search Results for " pb2 "

9

Compounds

Cat No. Product Name Synonyms Targets
T35889 PB2
PB2, a tris(2-carboxyethyl)phosphine (TCEP) analogue, enhances the survival of retinal ganglion cells (RGCs) following axotomy in vitro. Even at nanomolar and picomolar concentrations, PB2 demonstrates pronounced efficac...
T39176 PB28
PB28 is a cyclohexylpiperazine derivative that functions as a potent and highly selective agonist of the sigma 22) receptor, exhibiting a Ki (binding affinity) of 0.68 nM. At the same time, PB28 acts as an antagonist ...
T23122 PB28 dihydrochloride PB 28 dihydrochloride Others
σ2 receptor agonist
T4377 Pimodivir VX-787 Influenza Virus
Pimodivir (VX-787), an influenza A virus polymerases inhibitor via oral, interacts with the viral PB2 subunit.
T12526 PP7 Influenza Virus
PP7 is a potent inhibitor of PB1-PB2 interaction(IC50 of 8.6 μM).
T4377L Pimodivir HCl Pimodivir hydrochloride hemihydrate,Pimodivir hydrochloride
Pimodivir is an inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. The cell-based EC50 for VX-787 is 1.6 nM in a cytopathic effect (CPE) assay....
T83251 7-51A Influenza Virus
7-51A is an effective inhibitor of the PB2 subunit of the influenza RNA-dependent RNA polymerase (RdRP), with a dissociation constant (K_D) of 1.64 nM as determined by isothermal titration calorimetry (ITC).
T70207 Pimodivir tosylate
Pimodivir, also known as VX-787, JNJ-872, is a novel inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. VX-787 binds the cap-binding domain of ...
T36734 Methyl brevifolincarboxylate
Methyl brevifolincarboxylate (Brevifolincarboxylic acid methyl ester) is a potent influenza virus PB2 cap-binding inhibitor. Methyl brevifolincarboxylate exhibits inhibitory activity against influenza virus A/Puerto Rico...
TargetMol