3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T62809 | NLRP3-IN-7 | ||
NLRP3-IN-7 (Compound 36) is a selective inhibitor of the NLRP3 inflammasome and is able to assemble the NLRP3 inflammasome. | |||
T78168 | NLRP3-IN-17 | NOD-like Receptor (NLR) | |
NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM. It effectively inhibits NLRP3-dependent IL-1β secretion in mice, making it a valuable compound for... | |||
T71651 | GSK1370319A | ||
GSK1370319A is a potent P2X7 antagonist (IC50 = 3.2 nM). GSK1370319A inhibits ATP-induced increase in IL-1β release and caspase 1 activation in lipopolysaccharide (LPS)-primed mixed glia by blocking assembly of the infla... |