nlrp3-in-17 — TargetMol Chemicals

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Search Results for " nlrp3-in-17 "

Compounds

Cat No.	Product Name	Targets
T78168	NLRP3-IN-17	NOD-like Receptor (NLR)
	NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM. It effectively inhibits NLRP3-dependent IL-1β secretion in mice, making it a valuable compound for...	NOD-like Receptor (NLR)
T61709	AMS-17
	AMS-17 is a potent NLRP3 inhibitor, which effectively suppresses microglia activation both in vitro and in vivo. Additionally, AMS-17 exhibits inhibitory effects on various cytokines, such as caspase-1, TNF-α, IL-1β, and...
T60868	NF-κB-IN-4
	NF-κB-IN-4 (compound 17) is a potent inhibitor of NF-κB pathway which can cross blood brain barrier (BBB). NF-κB-IN-4 shows potential anti-neuroinflammatory activity with low toxicity which can be used for the research o...