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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T27135 | DDD85646 | DDD 85646,DDD-85646 | Parasite |
DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM. | |||
T23477 | Tris(dibenzylideneacetone)dipalladium | Tris DBA | Others |
tris(dibenzylideneacetone)dipalladium (Tris DBA) is a N-myristoyltransferase-1 (NMT-1) inhibitor | |||
T23973 | DDD100097 | DDD 100097,DDD-100097 | Others |
DDD100097 is a potent N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders. | |||
T63788 | PCLX-001 | Others | |
PCLX-001 is a small-molecule compound that acts as an orally active inhibitor of N-myristoyltransferase (NMT), specifically targeting NMT1 and NMT2 with IC50 values of 5 nM and 8 nM, respectively. This compound demonstra... | |||
T28596 | RO-09-4609 | RO 09-4609,RO09-4609,RO 094609,RO-094609 | |
RO-09-4609 is a potent and selective inhibitor of Candida albicans N-myristoyltransferase (CaNmt). | |||
T28701 | SC-58272 | SC58272 | |
SC-58272 is an inhibitor of N-myristoyltransferase (Nmt), a target for anti-fungal and anti-viral therapy. | |||
T70753 | PF00349412 | ||
PF00349412 is a selective inhibitor of protozoan protein N-myristoyltransferases. Inhibition of N-myristoyltransferase has been validated pre-clin. as a target for the treatment of fungal and trypanosome infections, usin... | |||
T68562 | FTR-1335 | ||
FTR1335 is a CaNMT inhibitor (IC50 = 0.49 nM) with good fungal selectivity. CaNMT inhibitors are fungicidal and show antifungal activity against Candida (especially fluconazole-resistant strains). They function by inhibi... | |||
T35691 | Myristoyl Coenzyme A (hydrate) | ||
Myristoyl coenzyme A (myristoyl-CoA) is a derivative of CoA that contains the long-chain fatty acid myristic acid . It is a substrate for N-myristoyltransferase during myristoylation, a process that adds a myristoyl grou... |