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Search Results for " n-myristoyltransferase "

9

Compounds

Cat No. Product Name Synonyms Targets
T27135 DDD85646 DDD 85646,DDD-85646 Parasite
DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.
T23477 Tris(dibenzylideneacetone)dipalladium Tris DBA Others
tris(dibenzylideneacetone)dipalladium (Tris DBA) is a N-myristoyltransferase-1 (NMT-1) inhibitor
T23973 DDD100097 DDD 100097,DDD-100097 Others
DDD100097 is a potent N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders.
T63788 PCLX-001 Others
PCLX-001 is a small-molecule compound that acts as an orally active inhibitor of N-myristoyltransferase (NMT), specifically targeting NMT1 and NMT2 with IC50 values of 5 nM and 8 nM, respectively. This compound demonstra...
T28596 RO-09-4609 RO 09-4609,RO09-4609,RO 094609,RO-094609
RO-09-4609 is a potent and selective inhibitor of Candida albicans N-myristoyltransferase (CaNmt).
T28701 SC-58272 SC58272
SC-58272 is an inhibitor of N-myristoyltransferase (Nmt), a target for anti-fungal and anti-viral therapy.
T70753 PF00349412
PF00349412 is a selective inhibitor of protozoan protein N-myristoyltransferases. Inhibition of N-myristoyltransferase has been validated pre-clin. as a target for the treatment of fungal and trypanosome infections, usin...
T68562 FTR-1335
FTR1335 is a CaNMT inhibitor (IC50 = 0.49 nM) with good fungal selectivity. CaNMT inhibitors are fungicidal and show antifungal activity against Candida (especially fluconazole-resistant strains). They function by inhibi...
T35691 Myristoyl Coenzyme A (hydrate)
Myristoyl coenzyme A (myristoyl-CoA) is a derivative of CoA that contains the long-chain fatty acid myristic acid . It is a substrate for N-myristoyltransferase during myristoylation, a process that adds a myristoyl grou...
TargetMol