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Search Results for " mtb-in-5 "

6

Compounds

Cat No. Product Name Synonyms Targets
T79561 Mtb-IN-5
Mtb-IN-5 (compound (-)17j) is an isoxazole exhibiting anti-Mycobacterium tuberculosis (Mtb) activity. It impedes Mtb respiration and biofilm formation within macrophages and augments the efficacy of the antibiotic isonia...
T79440 DprE1-IN-5
DprE1-IN-5 (Compound 10), a potent DprE1 inhibitor, exhibits anti-TB activity with an MIC of 4 μM against the Mtb H37Rv strain and demonstrates antimycobacterial efficacy against drug-resistant strains. Additionally, it ...
T61573 MtTMPK-IN-5
MtTMPK-IN-5 (compound 17) is a highly effective inhibitor of M. tuberculosis thymidylate kinase (Mtb TMPK), demonstrating remarkable enzyme inhibitory activity with an IC50 value of 34 μM. Additionally, MtTMPK-IN-5 exhib...
T61796 MtTMPK-IN-1
MtTMPK-IN-1 (compound 3) is a highly effective inhibitor of Mycobacterium tuberculosis thymidylate kinase (Mt TMPK), exhibiting an IC50 value of 2.5 μM. It displays moderate to weak activity against Mtb H37Rv while demon...
T62305 MtTMPK-IN-2
MtTMPK-IN-2 (compound 15), a potent inhibitor of Mycobacterium tuberculosis thymidylate kinase (Mt TMPK), demonstrates an IC50 value of 1.1 μM. This compound effectively inhibits Mtb H37Rv with a minimum inhibitory conce...
T62897 MtTMPK-IN-3
MtTMPK-IN-3 (compound 25) is a potent inhibitor of Mycobacterium tuberculosis thymidylate kinase (MtTMPK) with an IC50 value of 0.12 μM. It also demonstrates inhibitory activity against Mtb H37Rv with a MIC of 12.5 μM an...
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