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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T64049 | KIRA9 | ||
KIRA9 is a potent inhibitor of IRE1 with an IC50 value of 4.8 μM for INS-1 cells. KIRA9 completely binds the ATP binding site of IRE1 and blocks endoplasmic reticulum (ER) localised mRNA decay and apoptosis. |