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Search Results for " irak4-in-10 "

3

Compounds

Cat No. Product Name Synonyms Targets
T61931 IRAK4-IN-10
IRAK4-IN-10 (compound 75) is an effective IRAK4 inhibitor (IC50 is 1.5 nM), which can block the MyD88-dependent signal pathway. IRAK4-IN-10 has research potential in inflammatory diseases, autoimmune diseases and cancer.
T74670 KTX-951
KTX-951, a PROTAC designed for IRAK4 degradation (DC 50 =18 nM), exhibits an oral bioavailability (F%) of 22% in a rat model at a dosage of 10 mg/kg. Additionally, KTX-951 demonstrates promising anticancer potential [1].
T83866 LCC-12 formate
LCC-12, a derivative of the biguanide metformin, acts as a copper (II) chelator. It efficiently forms a monomeric bond with copper (II) and at 20 µM, it mitigates hydrogen peroxide-induced oxidation from NADH to NAD+. At...
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