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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T62271 | HER2-IN-9 | ||
HER2-IN-9 is an orally active HER2 inhibitor (IC50: 0.03 μM). HER2-IN-9 inhibits the proliferation and migration of HER-2-positive breast cancer cells and can be used in breast cancer research. | |||
T72854 | EGFR/HER2-IN-9 | ||
EGFR/HER2-IN-9, a compound inhibiting both EGFR and HER2, demonstrates potency with IC50 values of 3.2 nM for EGFR, 14 nM for HER2, and 8.3 nM against the EGFR T790M mutation. | |||
T80907 | TYVPANASL | ||
TYVPANASL, a nine-amino-acid MHC I-binding epitope from HER2/neu for CD8 T cells, can be utilized in the development of J-LEAPS vaccines [1]. | |||
T36648 | Tucatinib hemiethanolate | ||
Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Tucatinib hemiethanolate has nanomolar activity against purified HER2 enzyme and is approximately 500-f... | |||
T80906 | TYVPANASL TFA | ||
TYVPANASL TFA, a nine-amino-acid MHC I-binding CD8 T-cell epitope derived from HER2/neu, is utilized in the formulation of J-LEAPS vaccines [1]. |