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Cat No. | Product Name | Synonyms | Targets |
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T77450 | Vantictumab | OMP-18R5 | |
Vantictumab (OMP-18R5), a fully human IgG2 monoclonal antibody, antagonizes Wnt pathway signaling through binding to FZD1/2/5/7/8 receptors. It is currently under investigation for the treatment of various cancers, inclu... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00354 | FZD1/Frizzled 1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Frizzled homolog 1 (FZD1), also known as Frizzled-1, a member of the G-protein-coupled receptor superfamily, mediates Wnt signaling by serving as a co-receptor with LRP-5 for Wnt ligands. The FZD1 protein contains a sign... | |||
TMPY-01165 | FZD1/Frizzled 1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Frizzled-1, also known as FZD1, belongs to theG-protein coupled receptor Fz/Smo family. FZD1 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-term... |