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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11221 | ERAP1-IN-1 | Others | |
ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 allosterically activates ERAP1’s hydrolysis of fluorogenic and chromogenic amino acid substrates but competitively inhibits its activi... | |||
T69998 | DG046 | ||
DG046 is a novel potent phosphinic pseudopeptide ERAP1 inhibitor, binding in the ERAP1 active site, being stabilized by an unusual extensive network of π-stacking interactions | |||
T27160 | DG026 | DG 026,DG-026 | |
DG026 is a IRAP inhibitor. DG026 ables to selectively downregulate IRAP-dependent cross-presentation by dendritic cells but leave ERAP1-dependent cross-presentation unaffected. | |||
T63546 | DG013A | ||
DG013A is a mimetic inhibitor of hypophosphonic acid tripeptides, capable of acting on ERAP1 (IC50: 33 nM) and ERAP2 (IC50: 11 nM).DG013A can be used to study autoimmune diseases and cancer. |