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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T18601 | Desmethyl-QCA276 | PROTAC BRD4-binding moiety 4 | Others |
Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1]. |