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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T81171 | SH491 | ||
SH491 (Compound 33) serves as an antiosteoporosis agent, effectively inhibiting RANKL-induced osteoclast differentiation in bone-marrow-derived monocytes (BMMs) with an IC50 of 11.8 nM. Additionally, SH491 suppresses the... | |||
T64159 | Cathepsin K inhibitor 2 | ||
Cathepsin K inhibitor 2 is a potent inhibitor of cathepsin K. Cathepsin K (Cat K) is a cysteine protease expressed under the control of the CTSK gene, which is closely related to osteoporosis and hydrolyses collagen. cat... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01061 | Cathepsin K Protein, Human, Recombinant (His) | Human | E. coli |
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in... | |||
TMPH-02565 | Cathepsin K Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thy... | |||
TMPH-03262 | Cathepsin K Protein, Rat, Recombinant (His) | Rat | E. coli |
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in... |