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Search Results for " cc-1065 "

8

Compounds

Cat No. Product Name Synonyms Targets
T40810 Rachelmycin NSC298223,CC-1065
Rachelmycin (CC-1065; NSC 298223) is a potent naturally antibiotic isolated from Streptomyces zelensis . Rachelmycin binds non-covalently and covalently (N-3 adenine adduct) in the minor groove of B-form DNA. Rachelmycin...
T10701 (+)-CBI-CDPI2 Others
(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065.
T10974 DC41 Others
DC41 is a derivative of DC1. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylating agents, used for targeted treatment of cancer.
T10700 (+)-CBI-CDPI1 Others
(+)-CBI-CDPI1 is an enhanced functional analog of CC-1065. It is a DNA alkylating agent and an antibody-drug conjugates (ADCs) toxin.
T10973 DC41SMe Others
DC41SMe is a DC1 derivative that is cytotoxic to Ramos, Namalwa and HL60 / s with IC50s ranging from 18-25 pM. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylation molecules, used fo...
T10970 DC1 Others
DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer, is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065.
T68031 Adolezesin U 73975,Adozelesin ; U 73975,Adozelesin
https://pubmed.ncbi.nlm.nih.gov/1624543/
T10969 DC1SMe Others
DC1 is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065. DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer. DC1Sme is a DC1 derivative with IC50 ...
TargetMol