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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63091 | BChE-IN-5 | ||
BChE-IN-5 is a potent and selective inhibitor of BChE (IC50: 2.8 nM) and has a higher inhibitory effect on hBChE than hAChE. BChE-IN-5 has potential for use in Alzheimer's disease research. | |||
T60721 | AChE/BChE-IN-5 | ||
AChE/BChE-IN-5 (BMC-16) is an AChE and BChE dual inhibitor that can cross the BBB. The IC 50 values of AChE/BChE-IN-5 for human AChE (hAChE) and human BChE (hBChE) are 266 nM and 10.6 nM , respectively [1]. | |||
T63215 | COX-2-IN-22 | ||
COX-2-IN-22 is a COX-2 inhibitor (IC50: 8.6 μM) that can cross the blood-brain barrier and also exhibits inhibitory effects on AChE (IC50: 2.8 μM), BChE (IC50: 6.3 μM), β-Secretase (IC50: 15.3 μM), LOX-5 (IC50: 13.9 μM) ... | |||
T4700 | 1,3,5-Trihydroxy-4-prenylxanthone | ||
1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM; it shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylch... | |||
T36639 | Donecopride (fumarate hydrate) | ||
Donecopride is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT4E(Ki= 8.5 nM) and an inhibitor of acetylcholinesterase (AChE; IC50= 16 nM).1It is selective for AChE over butyrylcholinesterase (BChE; IC50= ... |