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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63039 | AKT-IN-13 | ||
AKT-IN-13 (compound 4b) is a potent inhibitor of Akt, acting on Akt1 (IC50: 1.6 nM), Akt2 (IC50: 2.4 nM) and Akt3 (IC50: 0.3 nM). AKT-IN-13 can be used in anticancer research. | |||
T35490 | 2-Amino-5-bromo-6-chloropyrazine | ||
2-Amino-5-bromo-6-chloropyrazine is a heterocyclic building block.1,2It has been used in the synthesis of Akt inhibitors. 1.Kettle, J.G., Brown, S., Crafter, C., et al.Diverse heterocyclic scaffolds as allosteric inhibit... | |||
T38263 | TBK1/IKKε-IN-4 | TBK1/IKKε-IN-4 | |
TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nM, respectively. This compound exhibits significantly reduced ... |