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Cat No. | Product Name | Synonyms | Targets |
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T62307 | Aha1/Hsp90-IN-1 | ||
Aha1/Hsp90-IN-1 (Compound 17) is an inhibitor of the Aha1/Hsp90 complex and has an inhibitory effect on tau protein aggregation.Aha1/Hsp90-IN-1 disrupts the Aha1/Hsp90 interaction (IC50: 3.32 μM). | |||
T69571 | SEW84 | ||
SEW84 is an inhibitor of Aha1-stimulated Hsp90(ASH) ATPase activity.SEW84 inhibits Aha1-stimulated Hsp90(ASH) activity with an IC50 value of 0.3 μM.SEW84 can be used in the study of protein deposition diseases. | |||
T63273 | KU-177 | ||
KU-177 is a potent Hsp90ATPase homolog 1 (Aha1) inhibitor that ablates Aha1-driven enhancement of Hsp90-dependent tau aggregation. 177 can impede the growth and induce apoptosis of cancer cells and can be used to study T... |
Cat No. | Product Name | Species | Expression System |
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TMPH-00887 | AHSA1 Protein, Human, Recombinant (GST) | Human | E. coli |
Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a re... |