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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63938 | AChE-IN-20 | ||
AChE-IN-20 is a potent inhibitor of AChE (IC50: 397.32 nM, Ki: 335.76 nM). AChE-IN-20 inhibits hCA-I (IC50: 84.14 nM, Ki: 97,86 nM), hCA-II (IC50: 69.24 nM, Ki: 76.23 nM) and α GLY (IC50: 52.08 nM, Ki: 57.93 nM). | |||
T78828 | AChE/BChE-IN-15 | ||
AChE/BChE-IN-15 (Compound 6d) serves as an inhibitor for both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), presenting inhibition constants (IC50) of 20 nM for AChE and 220 nM for BChE. It interacts with ... | |||
T62719 | AChE/BACE1/GSK3β-IN-1 | ||
AChE/BACE1/GSK3β-IN-1 is an orally active, blood-brain barrier-transparent, moderately bioavailable triple inhibitor of AChE/BACE1/GSK3β. AChE/BACE1/GSK3β-IN-1 can be used to study Alzheimer's disease (AD). | |||
T74690 | Monarsen | ||
Monarsen (EN101), a synthetic 20-base antisense oligodeoxynucleotide targeting the human AChE gene, is utilized in researching autoimmune myasthenia gravis (MG). This neuromuscular disorder is characterized by autoantibo... |