Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Selective ultrapotent PSEM (uPSEM) agonist for α7L131G,Q139L,Y217F-GlyR (PSAM4-GlyR) and PSAM4-5-HT3 chimeric ion channel agonist (EC50 values are 0.3 and 0.5 nM, respectively). Suppresses firing of layer 2/3 cortical neurons expressing PSAM4-GlyR in brain slices. Increases contralateral rotation in mice expressing PSAM4-GlyR unilaterally in the substantia nigra reticulata (LED 0.1 mg/kg).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 35 days | $ 615.00 | |
25 mg | 35 days | $ 2,360.00 |
Description | Selective ultrapotent PSEM (uPSEM) agonist for α7L131G,Q139L,Y217F-GlyR (PSAM4-GlyR) and PSAM4-5-HT3 chimeric ion channel agonist (EC50 values are 0.3 and 0.5 nM, respectively). Suppresses firing of layer 2/3 cortical neurons expressing PSAM4-GlyR in brain slices. Increases contralateral rotation in mice expressing PSAM4-GlyR unilaterally in the substantia nigra reticulata (LED 0.1 mg/kg). |
Molecular Weight | 419.434 |
Formula | C20H25N3O7 |
CAS No. | 2341833-14-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
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uPSEM 817 tartrate 2341833-14-3 uPSEM-817 Tartrate uPSEM817 Tartrate uPSEM 817 Tartrate inhibitor inhibit