Powder: -20°C for 3 years | In solvent: -80°C for 1 year
THR-β Agonist 6, a selective and orally active compound targeting the thyroid hormone receptor β (THR-β), demonstrates specificity with EC50 values of 0.03 μM for THR-β and 0.22 μM for THR-α. This compound boasts a remarkable liver-to-serum ratio of 93:1 in mouse models, underscoring its efficacy and potential for research in nonalcoholic steatohepatitis (NASH) [1].
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Description | THR-β Agonist 6, a selective and orally active compound targeting the thyroid hormone receptor β (THR-β), demonstrates specificity with EC50 values of 0.03 μM for THR-β and 0.22 μM for THR-α. This compound boasts a remarkable liver-to-serum ratio of 93:1 in mouse models, underscoring its efficacy and potential for research in nonalcoholic steatohepatitis (NASH) [1]. |
Molecular Weight | 457.27 |
Formula | C20H14Cl2N6O3 |
CAS No. | 2791290-58-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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THR-β agonist 6 2791290-58-7 inhibitor inhibit