Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rugonersen (RG6091; RO7248824), a locked-nucleic acid (LNA)-modified antisense oligonucleotide (ASO), reduces the silencing of ubiquitin-protein ligase E3A (UBE3A). This compound is significant in the research of Angelman syndrome (AS), a severe neurodevelopmental disorder resulting from the loss of neuronal E3 ligase UBE3A, demonstrating its utility in exploring treatments for AS [1] [2].
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Description | Rugonersen (RG6091; RO7248824), a locked-nucleic acid (LNA)-modified antisense oligonucleotide (ASO), reduces the silencing of ubiquitin-protein ligase E3A (UBE3A). This compound is significant in the research of Angelman syndrome (AS), a severe neurodevelopmental disorder resulting from the loss of neuronal E3 ligase UBE3A, demonstrating its utility in exploring treatments for AS [1] [2]. |
Molecular Weight | 6530 |
CAS No. | 2591587-57-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Rugonersen 2591587-57-2 inhibitor inhibit