Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Riluzole-13C,15N2 is intended for use as an internal standard for the quantification of riluzole by GC- or LC-MS. Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Formulations containing riluzole have been explored as therapeutics for slowing disease progression of amyotrophic lateral sclerosis.
Pack Size | Availability | Price/USD | Quantity |
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1 mg | 35 days | $ 891.00 |
Description | Riluzole-13C,15N2 is intended for use as an internal standard for the quantification of riluzole by GC- or LC-MS. Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Formulations containing riluzole have been explored as therapeutics for slowing disease progression of amyotrophic lateral sclerosis. |
Synonyms | Riluzole-13C,15N2 |
Molecular Weight | 237.18 |
Formula | C8H5F3N2OS |
CAS No. | 1215552-03-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chloroform: Soluble
Methanol: Soluble
You can also refer to dose conversion for different animals. More
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Riluzole-13C,15N2 1215552-03-6 Riluzole13C,15N2 Riluzole-13C,15N-2 Riluzole 13C,15N2 inhibitor inhibit