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pBD-1

Catalog No. TP2151   CAS 206367-33-1

pBD-1 is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites with the contribution of mucosal and systemic host defenses in pigs.

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pBD-1 Chemical Structure
pBD-1, CAS 206367-33-1
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Biological Description
Chemical Properties
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Description pBD-1 is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites with the contribution of mucosal and systemic host defenses in pigs.
Targets&IC50 bacterial:
In vitro In a northern blot analysis, pBD-1 mRNA only expresses in tongue epithelial tissues from 4-5 week-old pigs. In RT-PCR analysis, pBD-1 message throughout the epithelia of the respiratory (from the nasal septum to lung) and gastrointestinal (from the esophagus to rectum) tracts. In addition, it is detected in thymus, liver, kidney, urinary bladder, spleen, lymph node, brain, testis, skin, heart, muscle, bone marrow, alveolar macrophages, peripheral blood neutrophils, and the umbilical cord. The only cells that do not express pBD-1 are peripheral blood mononuclear cells.
Molecular Weight 7065.98
Formula C310H543N91O73S11
CAS No. 206367-33-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Zhang G, et al. Molecular cloning and tissue expression of porcine beta-defensin-1.FEBS Lett. 1998 Mar 6;424(1-2):37-40.

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Keywords

pBD-1 206367-33-1 Microbiology/Virology Antibacterial pBD 1 pBD1 inhibitor inhibit

 

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