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o-Iodohippurate sodium

Catalog No. T33785   CAS 133-17-5
Synonyms: Hippodin, NSC-63351, Sodium iodohippurate NSC 63351, NSC63351

o-Iodohippurate sodium is an analogue of p-aminohippuric acid used to determine effective renal plasma flow. Labelled OIH has a higher clearance than other radiopharmaceutical yet developed and is extremely suitable for renography. It is eliminated mainly by tubular secretion. In patients with normally functioning kidneys, 85% of the OIH may exist in the urine after intravenous injection for 30 minutes.

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o-Iodohippurate sodium Chemical Structure
o-Iodohippurate sodium, CAS 133-17-5
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Biological Description
Chemical Properties
Storage & Solubility Information
Description o-Iodohippurate sodium is an analogue of p-aminohippuric acid used to determine effective renal plasma flow. Labelled OIH has a higher clearance than other radiopharmaceutical yet developed and is extremely suitable for renography. It is eliminated mainly by tubular secretion. In patients with normally functioning kidneys, 85% of the OIH may exist in the urine after intravenous injection for 30 minutes.
Synonyms Hippodin, NSC-63351, Sodium iodohippurate NSC 63351, NSC63351
Molecular Weight 328.061
Formula C9H8INNaO3
CAS No. 133-17-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Mukai T, Fujioka Y, Arano Y, Saji H. [Design of radiolabeled antibody fragments for tumor-selective radioactivity localization--brush border enzyme-sensitive bond to decrease renal accumulation of radioactivity]. Yakugaku Zasshi. 2003 Aug;123(8):647-52. Review. Japanese. PubMed PMID: 12931660. 2. Fine EJ. Interventions in renal scintirenography. Semin Nucl Med. 1999 Apr;29(2):128-45. Review. PubMed PMID: 10321825. 3. Taylor A. Radionuclide renography: a personal approach. Semin Nucl Med. 1999 Apr;29(2):102-27. Review. PubMed PMID: 10321824. 4. el Maghraby TA, van Eck-Smit BL, de Fijter JW, Pauwels EK. Quantitative scintigraphic parameters for the assessment of renal transplant patients. Eur J Radiol. 1998 Oct;28(3):256-69. Review. PubMed PMID: 9881262.

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Keywords

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