Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Miravirsen (SPC-3649), a β-d-oxy-locked nucleic acid-modified phosphorothioate antisense oligonucleotide, inhibit the biogenesis of miR-122 . Miravirsen (SPC-3649) is used in the study for HCV infections.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | Inquiry | $ 1,520.00 |
Description | Miravirsen (SPC-3649), a β-d-oxy-locked nucleic acid-modified phosphorothioate antisense oligonucleotide, inhibit the biogenesis of miR-122 . Miravirsen (SPC-3649) is used in the study for HCV infections. |
In vitro | Miravirsen functions primarily by hybridizing with mature miR-122, thereby preventing its interaction with HCV RNA; this compound targets a sequence also found in pri- and pre-miR-122[1]. It attaches to the stem-loop structure of pri- and pre-miR-122 with high specificity (nanomolar affinity), inhibiting the miR-122 precursors' processing by both Dicer and Drosha[1]. |
Synonyms | SPC-3649, Miravirsen |
Molecular Weight | N/A |
CAS No. | 1072874-90-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Miravirsen 1072874-90-8 SPC3649 SPC 3649 SPC-3649 inhibitor inhibit