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YKL-06-061

Catalog No. T5576 CAS 2172617-15-9

YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.

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YKL-06-061, CAS 2172617-15-9

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.
Targets&IC50	SIK1:6.56 nM, SIK2:1.77 nM, SIK3:20.5 nM

Molecular Weight	527.673
Formula	C30H37N7O2
CAS No.	2172617-15-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 50 mg/mL (94.76 mM)

H2O: Insoluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19(11):2177-2184.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Autophagy Compound Library Anti-Lung Cancer Compound Library AMPK-Targeted Compound Library HIF-1 Signaling Pathway Compound Library Glycometabolism Compound Library Anti-Cancer Metabolism Compound Library Anti-Obesity Compound Library Lipid Metabolism Compound Library Anti-Pancreatic Cancer Compound Library

Related Products

Related compounds with same targets

WH-4-025 ARN-3236 YKL-06-061 HG-9-91-01 MRT 67307 dihydrochloride YKL-05-099

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

YKL-06-061 2172617-15-9 PI3K/Akt/mTOR信号通路 SIK AMPK YKL 06 061 Salt-inducible Kinase (SIK) inhibit Inhibitor YKL06061 inhibitor

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