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Vintoperol

Catalog No. T29107 CAS 106498-99-1

Synonyms: RT-3003, RGH2981, RGH 2981, RT3003, RT 3003, RGH-2981

Vintoperol, a calcium channel antagonist, is used potentially for the treatment of arterial occlusive disease and peripheral artery disease.

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Vintoperol, CAS 106498-99-1

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Vintoperol, a calcium channel antagonist, is used potentially for the treatment of arterial occlusive disease and peripheral artery disease.

Synonyms	RT-3003, RGH2981, RGH 2981, RT3003, RT 3003, RGH-2981
Molecular Weight	284.4
Formula	C18H24N2O
CAS No.	106498-99-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Yoshitsugu H, Fukuhara T, Ishibashi M, Nanbo T, Kagi N. Key fragments for identification of positional isomer pair in glucuronides from the hydroxylated metabolites of RT-3003 (Vintoperol) by liquid chromatography/electrospray ionization mass spectrometry. J Mass Spectrom. 1999 Oct;34(10):1063-8. PubMed PMID: 10510429. 2. Csomor K, Kárpáti E. Effect of vintoperol on platelet aggregation and experimental thrombosis. Arzneimittelforschung. 1994 Jan;44(1):36-40. PubMed PMID: 8135876. 3. Tkachenko MN, Sagach VF, Bazilyuk OV, Shapoval MV. Involvement of endothelium in vasodilating effects of vintoperol. J Cardiovasc Pharmacol. 1992;20 Suppl 12:S90-3. PubMed PMID: 1282997. 4. Sahach VF, Tkachenko MM, Bazyliuk OV. [The role of the endothelium in the vascular effects of vintoperol]. Fiziol Zh. 1992 May-Jun;38(3):32-9. Ukrainian. PubMed PMID: 1499759.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Vintoperol 106498-99-1 RT-3003 RGH2981 RGH 2981 RT3003 RT 3003 RGH-2981 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.