keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective, anti-cancer, antioxidant and anti-inflammatory activities, and DTL co-administration is more effective than either of the single agents in androgen-independent prostate cancer. Vicenin 2 might be a useful lead for the development of multiple target-oriented therapeutic modalities for the treatment of diabetes and diabetes-associated complications. Vicenin 2 could act as a UV light barrier to protect the plants.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 79.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 213.00 | |
25 mg | In stock | $ 359.00 | |
50 mg | In stock | $ 535.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 166.00 |
Description | Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective, anti-cancer, antioxidant and anti-inflammatory activities, and DTL co-administration is more effective than either of the single agents in androgen-independent prostate cancer. Vicenin 2 might be a useful lead for the development of multiple target-oriented therapeutic modalities for the treatment of diabetes and diabetes-associated complications. Vicenin 2 could act as a UV light barrier to protect the plants. |
Targets&IC50 | ACE:43.83 μM |
In vitro | Lychnophora salicifolia, commonly known as 'arnicão', is used as an anti-inflammatory agent and as a flavoring agent in the Brazilian traditional spirit 'cachaça'.METHODS AND RESULTS: In this work, the permeation process of Vicenin -2 (1) and lychnopholic acid (2) (major secondary metabolites from the hydroalcoholic extract) was investigated using Caco-2 cells. For this investigation, a new HPLC-DAD method was developed and validated for the quantification step. It was observed that 2 crosses the Caco-2 cell monolayer by passive diffusion. On the other hand, 1 was not transported, suggesting no absorption and no efflux of this compound in Caco-2 cells. |
Synonyms | Vicenin -2 |
Molecular Weight | 594.52 |
Formula | C27H30O15 |
CAS No. | 23666-13-9 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (92.51 mM)
You can also refer to dose conversion for different animals. More
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Vicenin 2 23666-13-9 Endocrinology/Hormones RAAS Vicenin -2 inhibit Vicenin2 Angiotensin-converting Enzyme (ACE) Inhibitor Vicenin-2 inhibitor