Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Verlukast is an (R)-enantiomer of MK-571 and a potent and selective LTD4 receptor antagonist. Verlukast showed [3H]leukotriene D4 binding in guinea-pig (IC50 = 3.1 +/- 0.5 nM) and human (IC50 = 8.0 +/- 3.0 nM) lung homogenates and dimethyl sulfoxide differentiated U937 cell membrane preparations (IC50 = 10.7 +/- 1.6 nM) but is essentially inactive versus [3H]leukotriene C4 binding in guinea-pig lung homogenates (IC50: 19 and 33 microM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | 6-8 weeks | $ 754.00 | |
100 mg | 6-8 weeks | $ 1,140.00 |
Description | Verlukast is an (R)-enantiomer of MK-571 and a potent and selective LTD4 receptor antagonist. Verlukast showed [3H]leukotriene D4 binding in guinea-pig (IC50 = 3.1 +/- 0.5 nM) and human (IC50 = 8.0 +/- 3.0 nM) lung homogenates and dimethyl sulfoxide differentiated U937 cell membrane preparations (IC50 = 10.7 +/- 1.6 nM) but is essentially inactive versus [3H]leukotriene C4 binding in guinea-pig lung homogenates (IC50: 19 and 33 microM). |
Synonyms | MK 0679, MK-679, L 668,019, MK 679, L 668019, L-668,019 |
Molecular Weight | 515.09 |
Formula | C26H27ClN2O3S2 |
CAS No. | 120443-16-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
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Verlukast 120443-16-5 L668019 MK 0679 MK-679 L-668019 MK679 MK0679 MK-0679 L 668,019 MK 679 L 668019 L-668,019 inhibitor inhibit