Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Validamycin A is an antifungal agent used to protect rice plants against sheath blight caused by the pathogenic fungus, R. solani, due to its ability to inhibit trehalase, a trehalose-hydrolizing enzyme (Ki = 1.9 nM; IC50 = 0.7 μM). It is also effective against the growth and sporulation of R. cerealis, F. culmorum, and other fungi. This compound has also been used to study trehalase activity and trehalose biosynthesis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | 5 days | Inquiry | |
100 mg | 5 days | Inquiry |
Description | Validamycin A is an antifungal agent used to protect rice plants against sheath blight caused by the pathogenic fungus, R. solani, due to its ability to inhibit trehalase, a trehalose-hydrolizing enzyme (Ki = 1.9 nM; IC50 = 0.7 μM). It is also effective against the growth and sporulation of R. cerealis, F. culmorum, and other fungi. This compound has also been used to study trehalase activity and trehalose biosynthesis. |
Targets&IC50 | Tyrosinase:Ki: 5.893 mM, Trehalase:72 μM (Antibiotic, IC50) |
Molecular Weight | 497.49 |
Formula | C20H35NO13 |
CAS No. | 37248-47-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBS (pH 7.2): 10 mg/mL
DMSO: 2 mg/mL
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Validamycin A 37248-47-8 inhibitor inhibit