Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VU6010572 is a highly potent and selective negative allosteric modulator of mGlu3, exhibiting an IC50 of 245 nM. Additionally, VU6010572 displays high central nervous system penetrance [1] [2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 2,140.00 | |
50 mg | 6-8 weeks | $ 2,785.00 | |
100 mg | 6-8 weeks | $ 3,520.00 |
Description | VU6010572 is a highly potent and selective negative allosteric modulator of mGlu3, exhibiting an IC50 of 245 nM. Additionally, VU6010572 displays high central nervous system penetrance [1] [2]. |
In vivo | VU6010572, administered intraperitoneally (i.p.) at a dosage of 3 mg/kg, demonstrates significant efficacy in CD-1 mice, exhibiting robust outcomes [1]. Moreover, when administered to rats at the same dosage and via the same route but observed after 45 minutes, VU6010572 induces enduring anxiolytic-like behavioral effects, highlighting its potent and lasting impact on anxiety-related behaviors [2]. |
Molecular Weight | 339.36 |
Formula | C20H18FNO3 |
CAS No. | 2126784-39-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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VU6010572 2126784-39-0 inhibitor inhibit