Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TMC647055 Choline Hydroxide Salt is a novel and potent non-nucleoside inhibitor of the HCV NS5B polymerase which potentially for the treatment of HCV infection. It has nanomolar cellular potency (EC(50) of 82 nM) with minimal associated cell toxicity (CC(50)<20 μM) and promising pharmacokinetic profiles in rats and dogs. TMC647055 showed promising in vitro biochemical, kinetic, and virological profile that is currently undergoing clinical evaluation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 102.00 | |
5 mg | In stock | $ 223.00 | |
10 mg | In stock | $ 321.00 | |
25 mg | In stock | $ 577.00 | |
50 mg | In stock | $ 825.00 | |
100 mg | In stock | $ 1,130.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 318.00 |
Description | TMC647055 Choline Hydroxide Salt is a novel and potent non-nucleoside inhibitor of the HCV NS5B polymerase which potentially for the treatment of HCV infection. It has nanomolar cellular potency (EC(50) of 82 nM) with minimal associated cell toxicity (CC(50)>20 μM) and promising pharmacokinetic profiles in rats and dogs. TMC647055 showed promising in vitro biochemical, kinetic, and virological profile that is currently undergoing clinical evaluation. |
Synonyms | TMC647055 Choline Hydroxide Salt (1204416-97-6 free base) |
Molecular Weight | 727.91 |
Formula | C37H53N5O8S |
CAS No. | T21537L |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/ml (82.43 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TMC647055 Choline Hydroxide Salt T21537L Microbiology/Virology Proteases/Proteasome HCV Protease TMC647055 Choline Hydroxide Salt (1204416-97-6 free base) 1204416-97-6 free base 1204416-97-6 TMC-647055 Choline Hydroxide Salt inhibitor inhibit