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Sulfolithocholic acid

Catalog No. T34743 CAS 34669-57-3

Synonyms: Lithocholic acid 3-alpha-sulfate

Sulfolithocholic acid is a bioactive chemical.

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Sulfolithocholic acid Chemical Structure

Sulfolithocholic acid, CAS 34669-57-3

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Sulfolithocholic acid is a bioactive chemical.

Synonyms	Lithocholic acid 3-alpha-sulfate
Molecular Weight	456.64
Formula	C24H40O6S
CAS No.	34669-57-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Jorge A, Fay O, Palazzi J, Sánchez D, Tanno H, Díaz M. [Determination of cholic and sulfolithocholic acids in various hepatopathies]. Acta Gastroenterol Latinoam. 1982;12(2):143-7. Spanish. PubMed PMID: 7158242. 2. Tanida N, Sawada K, Kawaura A, Oda M, Shimoyama T, Narisawa T. Effects of oral administration of sulfolithocholic acid disodium salt and lithocholic acid sodium salt on N-methyl-N-nitrosourea-induced colonic tumorigenesis in conventional rats. Cancer Res. 1989 Mar 1;49(5):1178-81. PubMed PMID: 2917349. 3. Bansal S, Lau AJ. Fast and sensitive quantification of human liver cytosolic lithocholic acid sulfation using ultra-high performance liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Feb 1;1011:171-8. doi: 10.1016/j.jchromb.2015.12.063. Epub 2016 Jan 4. PubMed PMID: 26773894. 4. Nakao K, Ohhara H, Taki T, Wakabayashi T, Ohgoh T. [Hepatotoxic effects of lithocholic acid and sulfolithocholic acid in rabbits (author's transl)]. Yakugaku Zasshi. 1980 Aug;100(8):792-8. Japanese. PubMed PMID: 7441488.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Sulfolithocholic acid 34669-57-3 Lithocholic acid 3-a-sulfate Lithocholic acid 3-α-sulfate Lithocholic acid 3-alpha-sulfate inhibitor inhibit

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