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Sinoporphyrin sodium

Catalog No. T28782 CAS 1820582-41-9

Synonyms: sinoporphyrin, DVDMS Free, DVDMS

Sinoporphyrin sodium significantly suppressed cell proliferation, promoted early apoptotic response, triggered collapse of F-actin filaments and inhibited cell migration. Sinoporphyrin sodium potentially a treatment for cancer. Sinoporphyrin sodium is also a photosensitizer.

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Sinoporphyrin sodium, CAS 1820582-41-9

Pack Size	Availability	Price/USD	Quantity
25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	sinoporphyrin, DVDMS Free, DVDMS
Molecular Weight	1235.314
Formula	C68H70N8Na4O9
CAS No.	1820582-41-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Shi R, Li C, Jiang Z, Li W, Wang A, Wei J. Preclinical Study of Antineoplastic Sinoporphyrin Sodium-PDT via In Vitro and In Vivo Models. Molecules. 2017 Jan 11;22(1). pii: E112. doi: 10.3390/molecules22010112. PubMed PMID: 28085075. 2. Shi R, Lin X, Zhang J, Jin H, Wang A, Wei J. Safety evaluation of repeated intravenous infusion of sinoporphyrin with and without PDT in rats. Photochem Photobiol Sci. 2016 Nov 2;15(11):1366-1376. PubMed PMID: 27714312. 3. Wu L, Wang X, Liu Q, Wingnang Leung A, Wang P, Xu C. Sinoporphyrin sodium mediated photodynamic therapy inhibits the migration associated with collapse of F-actin filaments cytoskeleton in MDA-MB-231 cells. Photodiagnosis Photodyn Ther. 2016 Mar;13:58-65. doi: 10.1016/j.pdpdt.2015.12.008. PubMed PMID: 26742781. 4. Yan X, Niu G, Lin J, Jin AJ, Hu H, Tang Y, Zhang Y, Wu A, Lu J, Zhang S, Huang P, Shen B, Chen X. Enhanced fluorescence imaging guided photodynamic therapy of sinoporphyrin sodium loaded graphene oxide. Biomaterials. 2015 Feb;42:94-102. doi: 10.1016/j.biomaterials.2014.11.040. PubMed PMID: 25542797; PubMed Central PMCID: PMC4280503.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Sinoporphyrin sodium 1820582-41-9 sinoporphyrin DVDMS Free DVDMS inhibitor inhibit

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