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Sarpagine

Catalog No. T20617 CAS 482-68-8

Synonyms: Raupin

Sarpagine is an alkaloid with the antihypertonic effect.

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Sarpagine, CAS 482-68-8

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5 mg	Inquiry	$ 1,590.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Sarpagine is an alkaloid with the antihypertonic effect.

Synonyms	Raupin
Molecular Weight	310.39
Formula	C19H22N2O2
CAS No.	482-68-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

References and Literature

1. Namjoshi OA, Cook JM. Sarpagine and Related Alkaloids. Alkaloids Chem Biol. 2016;76:63-169. doi: 10.1016/bs.alkal.2015.08.002. Epub 2015 Oct 9. Review. PubMed PMID: 26827883; PubMed Central PMCID: PMC4864735. 2. Lim SH, Low YY, Sinniah SK, Yong KT, Sim KS, Kam TS. Macroline, akuammiline, sarpagine, and ajmaline alkaloids from Alstonia macrophylla. Phytochemistry. 2014 Feb;98:204-15. doi: 10.1016/j.phytochem.2013.11.014. Epub 2013 Dec 13. PubMed PMID: 24342109. 3. Tan SJ, Lim JL, Low YY, Sim KS, Lim SH, Kam TS. Oxidized derivatives of macroline, sarpagine, and pleiocarpamine alkaloids from Alstonia angustifolia. J Nat Prod. 2014 Sep 26;77(9):2068-80. doi: 10.1021/np500439u. Epub 2014 Sep 11. PubMed PMID: 25211145. 4. Krüger S, Gaich T. Enantioselective, protecting-group-free total synthesis of sarpagine alkaloids--a generalized approach. Angew Chem Int Ed Engl. 2015 Jan 2;54(1):315-7. doi: 10.1002/anie.201407280. Epub 2014 Oct 24. PubMed PMID: 25346454.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Sarpagine 482-68-8 Raupin inhibitor inhibit

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