Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Salvinorin A propionate is a selective partial agonist at κ1-opioid receptors (KOR) with a Ki value of 32.6 nM. It inhibits adenylate cyclase (EC50 = 4.7 nM) in HEK293 cells transfected with human KOR. It is selective for KORs over μ, δ, and ORL-1 opioid receptors and has no effect at serotonin, dopamine, muscarinic, or adrenergic receptors. In mice, salvinorin A propionate (13 μg, i.c.v.) reduces nociceptive responses in a radiant heat tail-flick assay, though not as potently as salvinorin A .
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 110.00 | |
5 mg | 35 days | $ 483.00 | |
10 mg | 35 days | $ 853.00 |
Description | Salvinorin A propionate is a selective partial agonist at κ1-opioid receptors (KOR) with a Ki value of 32.6 nM. It inhibits adenylate cyclase (EC50 = 4.7 nM) in HEK293 cells transfected with human KOR. It is selective for KORs over μ, δ, and ORL-1 opioid receptors and has no effect at serotonin, dopamine, muscarinic, or adrenergic receptors. In mice, salvinorin A propionate (13 μg, i.c.v.) reduces nociceptive responses in a radiant heat tail-flick assay, though not as potently as salvinorin A . |
Molecular Weight | 446.49 |
Formula | C24H30O8 |
CAS No. | 689295-71-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL
DMF: 2 mg/mL
Acetonitrile: 1 mg/mL
DMSO: 1 mg/mL
You can also refer to dose conversion for different animals. More
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Salvinorin A Propionate 689295-71-4 inhibitor inhibit