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SR 42128

Catalog No. T34704 CAS 98092-14-9

Synonyms: SR-42128, SR42128

SR 42128 is arginine salt.

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SR 42128, CAS 98092-14-9

Pack Size	Availability	Price/USD	Quantity
25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

SR 42128 is arginine salt.

Synonyms	SR-42128, SR42128
Molecular Weight	747.975
Formula	C39H65N5O9
CAS No.	98092-14-9

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Delie F, Couvreur P, Nisato D, Michel JB, Puisieux F, Letourneux Y. Synthesis and in vitro study of a diglyceride prodrug of a peptide. Pharm Res. 1994 Aug;11(8):1082-7. PubMed PMID: 7971705. 2. Cumin F, Nisato D, Gagnol JP, Corvol P. A potent radiolabeled human renin inhibitor, [3H]SR42128: enzymatic, kinetic, and binding studies to renin and other aspartic proteases. Biochemistry. 1987 Dec 1;26(24):7615-21. PubMed PMID: 3322402. 3. Gougat J, Canat S, Lacour C, Cazaubon C, Gagnol J, Nisato D. [Increase in plasma levels of active and inactive renin after inhibition of renin activity by SR 42128 in conscious Macaca monkeys]. Arch Mal Coeur Vaiss. 1987 Jun;80(6):875-8. French. PubMed PMID: 3116988. 4. Chansel D, Dussaule JC, Ardaillou N, Ardaillou R. Identification and regulation of renin in human cultured mesangial cells. Am J Physiol. 1987 Jan;252(1 Pt 2):F32-8. PubMed PMID: 3544867.

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

SR 42128 98092-14-9 SR-42128 SR42128 inhibitor inhibit

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