Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SHS4121705 is an orally bioavailable mitochondrial uncoupler.1It increases oxygen consumption rate in L6 rat myoblast cells with an EC50value of 4.3 μM. SHS4121705 (25 mg/kg per day in the diet) reduces hepatic steatosis, liver triglyceride levels, and plasma alanine aminotransferase (ALT) levels in Stelic animal model (STAM) mice, a model of non-alcoholic steatohepatitis (NASH).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 293.00 | |
5 mg | 35 days | $ 460.00 | |
10 mg | 35 days | $ 838.00 |
Description | SHS4121705 is an orally bioavailable mitochondrial uncoupler.1It increases oxygen consumption rate in L6 rat myoblast cells with an EC50value of 4.3 μM. SHS4121705 (25 mg/kg per day in the diet) reduces hepatic steatosis, liver triglyceride levels, and plasma alanine aminotransferase (ALT) levels in Stelic animal model (STAM) mice, a model of non-alcoholic steatohepatitis (NASH). |
Molecular Weight | 313.19 |
Formula | C11H6F3N5O3 |
CAS No. | 2379550-82-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 30 mg/mL
DMSO: 25 mg/mL
DMF: 10 mg/mL
You can also refer to dose conversion for different animals. More
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SHS4121705 2379550-82-8 SHS-4121705 SHS 4121705 inhibitor inhibit