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S 9871

Catalog No. T34470 CAS 91403-55-3

Synonyms: RX-801080, RX 801080, S9871, RX801080, S-9871

S 9871, also known as RX 801080, is an imidazoline derivative reported to antagonize imidazoline-stimulated insulin secretion.

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S 9871, CAS 91403-55-3

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

S 9871, also known as RX 801080, is an imidazoline derivative reported to antagonize imidazoline-stimulated insulin secretion.

Synonyms	RX-801080, RX 801080, S9871, RX801080, S-9871
Molecular Weight	188.23
Formula	C11H12N2O
CAS No.	91403-55-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Pauwels PJ, Rauly I, Wurch T. Dissimilar pharmacological responses by a new series of imidazoline derivatives at precoupled and ligand-activated alpha 2A-adrenoceptor states: evidence for effector pathway-dependent differential antagonism. J Pharmacol Exp Ther. 2003 Jun;305(3):1015-23. Epub 2003 Mar 20. PubMed PMID: 12649300. 2. Ball AJ, Flatt PR, McClenaghan NH. Stimulation of insulin secretion in clonal BRIN-BD11 cells by the imidazoline derivatives KU14r and RX801080. Pharmacol Res. 2000 Dec;42(6):575-9. PubMed PMID: 11058411. 3. Chan SL, Atlas D, James RF, Morgan NG. The effect of the putative endogenous imidazoline receptor ligand, clonidine-displacing substance, on insulin secretion from rat and human islets of Langerhans. Br J Pharmacol. 1997 Mar;120(5):926-32. PubMed PMID: 9138700; PubMed Central PMCID: PMC1564530. 4. Morgan NG, Chan SL, Brown CA, Tsoli E. Characterization of the imidazoline binding site involved in regulation of insulin secretion. Ann N Y Acad Sci. 1995 Jul 12;763:361-73. Review. PubMed PMID: 7677348.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

S 9871 91403-55-3 RX-801080 RX 801080 S9871 RX801080 S-9871 inhibitor inhibit

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