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Rostaporfin

Catalog No. T34393 CAS 284041-10-7

Synonyms: SnET2, tin etiopurpurin dichloride, tin ethyl etiopurpurin dichloride, Purlytin, Sn(IV) etiopurpurin

Rostaporfin (also known as REM-001, tin ethyl etiopurpurin, Sn(IV) etiopurpurin, Purlytin, SnET2), is a synthetic purpurin with photosensitizing activity. Rostaporfin preferentially accumulates in tumor cells due to an increased rate of metabolism. Upon exposure to a light source, this agent absorbs light, forming an extended high energy conformational state that produces high quantum yields of singlet oxygen with local cytotoxic effects.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Rostaporfin, CAS 284041-10-7

Pack Size	Availability	Price/USD	Quantity
25 mg	6-8 weeks	$ 1,520.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	SnET2, tin etiopurpurin dichloride, tin ethyl etiopurpurin dichloride, Purlytin, Sn(IV) etiopurpurin
Molecular Weight	764.37
Formula	C37H42Cl2N4O2Sn
CAS No.	284041-10-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Sivaprasad S, Hykin P. The role of photodynamic therapy in ophthalmology. Br J Hosp Med (Lond). 2006 Dec;67(12):647-50. Review. PubMed PMID: 17328448. 2. Chakravarthy U, Soubrane G, Bandello F, Chong V, Creuzot-Garcher C, Dimitrakos SA 2nd, Korobelnik JF, Larsen M, MonÃ©s J, Pauleikhoff D, Pournaras CJ, Staurenghi G, Virgili G, Wolf S. Evolving European guidance on the medical management of neovascular age related macular degeneration. Br J Ophthalmol. 2006 Sep;90(9):1188-96. PubMed PMID: 16929063; PubMed Central PMCID: PMC1857411. 3. Jankun J, Keck RW, Skrzypczak-Jankun E, Lilge L, Selman SH. Diverse optical characteristic of the prostate and light delivery system: implications for computer modelling of prostatic photodynamic therapy. BJU Int. 2005 Jun;95(9):1237-44. PubMed PMID: 15892808. 4. Skrzypczak-Jankun E, Borbulevych OY, Melillo A, Keck R, Soriano-Garcia M, Aniola J, Niedre M, Lilge L, Selman SH, Jankun J. Aspirin blocks binding of photosensitizer SnET2 into human serum albumin: implications for photodynamic therapy. Int J Mol Med. 2005 May;15(5):777-83. PubMed PMID: 15806298.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Rostaporfin 284041-10-7 tin ethyl etiopurpurin Dichloride tin etiopurpurin Dichloride SnET2 tin etiopurpurin dichloride tin ethyl etiopurpurin dichloride tin etiopurpurin Purlytin tin ethyl etiopurpurin Sn(IV) etiopurpurin inhibitor inhibit

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